Crospovidone

1. Product Overview

Crospovidone is a highly cross-linked, insoluble form of polyvinylpyrrolidone (PVP) widely used as a high-performance pharmaceutical excipient. Its primary industrial function is as a superdisintegrant, enabling tablets and solid dosage forms to break down rapidly and consistently for efficient active-ingredient release. Its strong swelling capacity, low solubility, and excellent compatibility support reliable tablet manufacturing and formulation performance. Crospovidone is strategically important for pharmaceutical manufacturers seeking consistent quality, improved dissolution performance, and dependable large-volume excipient supply.

2. Key Specifications & Technical Characteristics

• Chemical composition: Cross-linked polyvinylpyrrolidone (crospovidone)
• Grade: Pharmaceutical / excipient grade
• Purity: Typically high-purity material suitable for pharmaceutical formulation, subject to applicable pharmacopeial specification
• Physical form: White to off-white, free-flowing powder
• Solubility: Insoluble in water while capable of rapid swelling
• Functional characteristics: High capillary activity, rapid swelling, excellent wicking and disintegration performance
• Particle size: Available in controlled particle-size grades according to manufacturer specification
• Packaging options: Typically 20–25 kg bags or fiber drums; customized bulk packaging may be available
• Shelf life: Typically 24–36 months when stored in sealed original packaging under recommended conditions
• Storage: Store in a cool, dry, well-ventilated environment, protected from moisture and contamination
• Origin: Available from qualified international manufacturing sources, subject to supply availability and buyer requirements

3. Core Industrial Applications

• Pharmaceutical manufacturing: Used as a superdisintegrant in immediate-release tablets and capsules.
• Direct-compression formulations: Supports rapid tablet breakup while maintaining efficient manufacturing performance.
• Dissolution enhancement: Promotes rapid penetration of liquid into tablets, helping accelerate disintegration and active-ingredient release.
• Oral solid dosage forms: Suitable for a broad range of pharmaceutical formulations due to its chemical stability and compatibility.
• Operational advantage: Its rapid wicking and swelling action can provide more consistent disintegration than conventional starch-based disintegrants in many formulations.
• Manufacturing efficiency: Effective at relatively low formulation concentrations, supporting optimized excipient utilization and consistent tablet performance.

4. Competitive Advantages

• Quality consistency: Controlled physical and functional characteristics support repeatable pharmaceutical formulation performance.
• High functional efficiency: Rapid disintegration properties can improve dissolution and dosage-form performance.
• Supply reliability: Suitable for planned procurement programs and recurring pharmaceutical manufacturing requirements.
• Logistics capability: Available in export-ready packaging with bulk supply options for international B2B procurement.
• Price competitiveness: Competitive sourcing supports cost-efficient procurement for pharmaceutical manufacturers and distributors.
• Technical documentation: Certificate of Analysis (CoA), specification sheets, Safety Data Sheets (SDS), and relevant quality documentation can be provided subject to supplier availability.
• Strategic sourcing value: A dependable excipient solution for manufacturers seeking consistent quality, scalable supply, and optimized procurement economics.

5. Commercial & Supply Information

• Minimum Order Quantity (MOQ): BULK 20MT
• Loading Capacity: Subject to packaging configuration, container type, and applicable shipping requirements
• Supply Format: Bulk commercial supply for pharmaceutical manufacturers, distributors, formulators, and international buyers